5-甲基-2'-脱氧-6-氮杂尿苷合成路线 （共 4 条）
反应条件
1: With sodium methylate in methanol T=20°C; 6 h; 2: in methanol
参考文献
Koegler, Martin; Busson, Roger; De Jonghe, Steven; Rozenski, Jef; Van Belle, Kristien; Louat, Thierry; Munier-Lehmann, Helne; Herdewijn, Piet
Chemistry and Biodiversity, 2012 , vol. 9, # 3 p. 536 - 556
反应条件
streptococcus faecalis
参考文献
Hall; Haselkorn
Journal of the American Chemical Society, 1958 , vol. 80, p. 1138,1139,1140
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Prusoff
Journal of Biological Chemistry, 1955 , vol. 215, p. 809,812-817
反应条件
1: 40 percent / pyridine / 1 h / 100 °C 2: pyridine / 20 h / 4 °C 3: 33 percent / LiN3 / dimethylformamide / 2 h / 130 °C 4: 86 percent / acetic acid / 0.33 h / 100 °C View Scheme
参考文献
Lin, Tai-Shun; Guo, Ji-Yu; Schinazi, Raymond F.; Chu, Chung K.; Xiang, Jia-Ning; Prusoff, Willian H.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 2 p. 336 - 340
反应条件
phosphate buffer; thymidine phosphorylase pH=6.8; 168 h;
参考文献
Hatano, Akihiko; Harano, Aiko; Takigawa, Yoshikatsu; Naramoto, Yasuhiro; Toda, Keisuke; Nakagomi, Yuuichi; Yamada, Hideyuki
Bioorganic and Medicinal Chemistry, 2008 , vol. 16, # 7 p. 3866 - 3870
