Coenzyme A Enzymatic reaction;

1: water 2: Pseudomonas quinolone signal D from strain PA14 in Escherichia coli / Enzymatic reaction View Scheme

<b>Multi-step reaction with 4 steps<br /> </b>1.1: lithium diisopropyl amide / tetrahydrofuran / 0.25 h / -78 &deg;C / |Inert atmosphere<br />1.2: 4 h / -78 - 20 &deg;C<br />2.1: sodium tetrahydroborate / methanol / 0.33 h / 0 &deg;C<br />3.1: dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 0 - 20 &deg;C / |Inert atmosphere<br />4.1: pyridinium chlorochromate / dichloromethane / 2 h / 20 &deg;C<br /> <br /> &nbsp;