4-((叔丁基二甲基甲硅烷基)氧基)-3-氧代丁酸乙酯合成路线 （共 3 条）
反应条件
1: ethyl γ-hydroxyacetoacetate With 1H-imidazole; 4-(N,N-dimethlyamino)pyridine in dichloromethane T=0°C; 2: tert-butyldimethylsilyl chloride in dichloromethane T=0 - 20°C;
参考文献
Fan, Weizheng; Li, Wanfang; Ma, Xin; Tao, Xiaoming; Li, Xiaoming; Yao, Ying; Xie, Xiaomin; Zhang, Zhaoguo
Journal of Organic Chemistry, 2011 , vol. 76, # 22 p. 9444 - 9451
反应条件
1.1: sodium hydride / tetrahydrofuran / 12.5 h / 20 °C 2.1: palladium 10 on activated carbon; hydrogen / ethyl acetate / 5 h / 20 °C / 7500.75 Torr / Autoclave 3.1: 1H-imidazole; 4-(N,N-dimethlyamino)pyridine / dichloromethane / 0 °C 3.2: 0 - 20 °C View Scheme
参考文献
Fan, Weizheng; Li, Wanfang; Ma, Xin; Tao, Xiaoming; Li, Xiaoming; Yao, Ying; Xie, Xiaomin; Zhang, Zhaoguo
Journal of Organic Chemistry, 2011 , vol. 76, # 22 p. 9444 - 9451
反应条件
1.1: palladium 10 on activated carbon; hydrogen / ethyl acetate / 5 h / 20 °C / 7500.75 Torr / Autoclave 2.1: 1H-imidazole; 4-(N,N-dimethlyamino)pyridine / dichloromethane / 0 °C 2.2: 0 - 20 °C View Scheme
参考文献
Fan, Weizheng; Li, Wanfang; Ma, Xin; Tao, Xiaoming; Li, Xiaoming; Yao, Ying; Xie, Xiaomin; Zhang, Zhaoguo
Journal of Organic Chemistry, 2011 , vol. 76, # 22 p. 9444 - 9451
