1: 4-methyl-morpholine / acetonitrile / 0.17 h / 20 °C 2: 1H-tetrazole / acetonitrile / 3 h / 20 °C 3: tert.-butylhydroperoxide / water; acetonitrile / 0.17 h / 20 °C 4: water; acetic acid / tetrahydrofuran / 1 h / 20 °C View Scheme

1: 1H-tetrazole / acetonitrile / 3 h / 20 °C 2: tert.-butylhydroperoxide / water; acetonitrile / 0.17 h / 20 °C 3: water; acetic acid / tetrahydrofuran / 1 h / 20 °C View Scheme

1: aq. CH3COOH 2: tert-butyl hydroperoxide View Scheme

1: aq. CH3COOH 2: tert-butyl hydroperoxide View Scheme

Yield given. Multistep reaction;

piperidine in N,N-dimethyl-formamide 20percent conc. of amine; Product distribution;