1: KOH 2: Zn / acetonitrile View Scheme

1: With tert.-butyl lithium in diethyl ether; pentane T=-78°C; 3 h; Cooling with acetone-liquid nitrogen; 2: With boric acid trimethyl ester in diethyl ether; pentane 3: With hydrogenchloride; water in diethyl ether; pentane

under N2;

1: TFVE With tert.-butyl lithium in diethyl ether; pentane T=-78°C; 2: carbon dioxide in diethyl ether; pentane T=-78 - 20°C; 1.25 h;