反应条件
1: 74 percent / NaHCO3 / methanol / 2.5 h / Ambient temperature 2: 1.) 1,1'-(thiocarbonyl)diimidazole, 2.) AIBN, tri-n-butyltin hydride / 1.) acetonitrile, 45 deg C, 24 h, 2.) toluene, reflux, 1 h 3: 73 percent / aq. LiOH / methanol / 7 h / Ambient temperature View Scheme
参考文献
Montgomery, John A.; Shortnacy-Fowler, Anita T.; Clayton, Sarah D.; Riordan, James M.; Secrist, John A.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 2 p. 397 - 401
