1-(3-氯-4-氟苯基)-吡咯-2,5-二酮合成路线 （共 4 条）
反应条件
1: in diethyl ether T=20°C; 2: With sodium acetate; acetic anhydride T=120°C;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 9 p. 2876 - 2879
反应条件
sodium acetate in acetic anhydride T=20 - 100°C; 0.5 h;
参考文献
Budke, Brian; Kalin, Jay H.; Pawlowski, Michal; Zelivianskaia, Anna S.; Wu, Megan; Kozikowski, Alan P.; Connell, Philip P.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 1 p. 254 - 263
反应条件
1: diethyl ether / 2 h / 20 °C 2: sodium acetate / acetic anhydride / 0.5 h / 20 - 100 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 56, # 1 p. 254 - 263
参考文献
Abramovitch, Rudolph A.; Mathur, Suchet S.; Saunders, Daniel W.; Vanderpool, Danny P.
Tetrahedron Letters, 1980 , vol. 21, p. 705 - 708
