SPhos; C16H16Cl2N2O4Pd2; N-hexadecyl-N,N,N-trimethylammonium bromide; triethylamine in water T=130°C; Sonogashira Cross-Coupling; 0.5 h; Microwave irradiation;

C26H16Cl6N2O2Pd2; tetrabutylammomium bromide; potassium hydroxide in methanol; water T=110°C; Suzuki coupling; 0.333333 h; Microwave irradiation;