反应条件
1: 83 percent / Et3N / CH2Cl2 / 1 h / 0 deg C to r.t.
2: 95 percent / K2CO3, KI / acetone / 3 h
3: HCl / methanol / 1 h / Heating
4: NaCNBH3 / methanol / 1 h / Heating
5: K2CO3, KI / acetone / 16 h
6: 1) LDA, 2) HCl / 1) THF/hexane, -50 deg C, 30 min, 2) reflux, 4 h
View Scheme
参考文献
Branden, Stefan Van den; Compernolle, Frans; Hoornaert, Georges J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 8 p. 1035 - 1042
