1H-苯并咪唑-2-硫醇合成路线 （共 177 条）
反应条件
1: 20 percent / H2SO4 / acetic acid / 3 h / 84 °C 2: 60 percent / 85percent m-CPBA / CHCl3 / 0.5 h / -10 °C View Scheme
参考文献
Adelstein, Gilbert W.; Yen, Chung H.; Haack, Richard A.; Yu, Stella; Gullikson, Gary; et al.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 6 p. 1215 - 1220
反应条件
sodium hydroxide in water 4 h; Heating;
参考文献
Synthetic Communications, , vol. 38, # 20 p. 3477 - 3489
参考文献
Adelstein, Gilbert W.; Yen, Chung H.; Haack, Richard A.; Yu, Stella; Gullikson, Gary; et al.
Journal of Medicinal Chemistry, 1988 , vol. 31, # 6 p. 1215 - 1220
参考文献
NIPPON CHEMIPHAR CO., LTD.
Patent: EP218336 B1, 1991 ;
反应条件
sodium hydroxide in water T=15 - 75°C;
参考文献
Reddy, Ganta Madhusudhan; Mukkanti, Kaga; Bhaskar, Boluggodu Vijaya; Reddy, Padi Pratap
Synthetic Communications, 2009 , vol. 39, # 2 p. 278 - 290
反应条件
sodium hydride 1.) DMF, 2.) DMF, 70 deg C, 10h, irradiation; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Journal of Fluorine Chemistry, , vol. 51, # 1 p. 21 - 32
反应条件
dihydrogen peroxide; trichlorophosphate in water T=80°C; 1.33333 h; Micellar solution;
参考文献
Bahrami, Kiumars; Khodaei, Mohammad M.; Abbasi, Jamshid
Synthesis, 2012 , vol. 2012, # 2 p. 316 - 322
反应条件
hydrogen bromide; bromine; acetic acid Bromination;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 22 p. 2509 - 2512
反应条件
triethylamine in acetonitrile T=20°C; 12 h;
参考文献
Radl, Stanislav; Klecan, Ondrej; Havlicek, Jaroslav
Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 6 p. 1447 - 1453
反应条件
Multistep reaction. Further byproducts given;
参考文献
Pingili, R. Reddy; Jambula, M. Reddy; Ganta, M. Reddy; Ghanta, M. Reddy; Sajja; Sundaram; Boluggdu, V. Bhaskar
Pharmazie, 2005 , vol. 60, # 11 p. 814 - 818
