1H-苯并咪唑-2-硫醇合成路线 （共 177 条）
反应条件
pyridine in dichloromethane
24 h; other thiols, other sulfonyl chlorides; Product distributionMechanism;
参考文献
Mahieu, Jean-Pierre; Gosselet, Martine; Sebille, Bernard; Beuzard, Yves
Synthetic Communications, 1986 , vol. 16, # 13 p. 1709 - 1722
反应条件
reconstructed hydrotalcite in dimethyl sulfoxide
T=70°C; 1 h; Microwave irradiationCooling;
参考文献
Cruz-Gonzalez, Deysi Y.; Gonzalez-Olvera, Rodrigo; Angeles-Beltran, Deyanira; Negron-Silva, Guillermo E.; Santillan, Rosa
Synthesis (Germany), 2013 , vol. 45, # 23 p. 3281 - 3287
反应条件
1: sodium hydroxide / ethanol; H2O / 2.5 h / Heating
2: m-chloroperbenzoic acid / CHCl3 / 0.17 h / 0 - 5 °C
3: aq. ethanol / 25 °C
View Scheme
参考文献
Graber, David R.; Morge, Raymond A.; Sih, John C.
Journal of Organic Chemistry, 1987 , vol. 52, # 20 p. 4620 - 4622
反应条件
sodium hydroxide in ethanol; water
2.5 h; Heating;
参考文献
Graber, David R.; Morge, Raymond A.; Sih, John C.
Journal of Organic Chemistry, 1987 , vol. 52, # 20 p. 4620 - 4622
反应条件
copper(l) iodide; tetrabutyl ammonium fluoride; N-methyl-2-(methylamino)ethylamine in water; N,N-dimethyl-formamide
T=65°C; 12 h;
参考文献
Xu, Hui; Gu, Shaojin; Chen, Wanzhi; Li, Dacheng; Dou, Jianmin
Journal of Organic Chemistry, 2011 , vol. 76, # 8 p. 2448 - 2458
反应条件
1: H2O
2: H2SO4
View Scheme
参考文献
Ogura,H. et al.
Chemical and Pharmaceutical Bulletin, 1968 , vol. 16, # 11 p. 2167 - 2171
反应条件
1: NaOH, 30percent H2O2 / H2O
2: 68.1 percent / 3 h / 160 - 170 °C
View Scheme
参考文献
Popov, I. I.; Boroshko, S. L.; Tertov, B. A.; Makarov, S. P.; Simonov, A. M.; Simkin, B. Ya.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1987 , vol. 23, # 12 p. 1348 - 1352
Khimiya Geterotsiklicheskikh Soedinenii, 1987 , # 12 p. 1673 - 1677
反应条件
trichlorophosphate
T=110°C;
参考文献
Deng, Xiaohu; Roessler, Armin; Brdar, Ivana; Faessler, Roger; Wu, Jiejun; Sales, Zachary S.; Mani, Neelakandha S.
Journal of Organic Chemistry, 2011 , vol. 76, # 20 p. 8262 - 8269
反应条件
sodium hydroxide in dichloromethane; water
参考文献
Hoffman-La Roche Inc.
Patent: US4766133 A1, 1988 ;
反应条件
sodium hydroxide in methanol
Heating;
参考文献
Kuehler, Thomas C.; Swanson, Marianne; Shcherbuchin, Vladimir; Larsson, Hakan; Mellgard, Bjoern; Sjoestroem, Jan-Eric
Journal of Medicinal Chemistry, 1998 , vol. 41, # 11 p. 1777 - 1788
