1H-苯并咪唑-2-硫醇合成路线 (共 177 条)
反应条件
N-ethyl-N,N-diisopropylamine in tetrahydrofuran
17 h; Heating;
参考文献
Matthews, Craig J.; Clegg, William; Elsegood, Mark R. J.; Leese, Troy A.
Journal of the Chemical Society - Dalton Transactions, 1996 , # 8 p. 1531 - 1538
反应条件
1: 65 percent / NaOH / H2O / Heating
2: 70 percent / Ac2O, Py
3: 50 percent / NaOAc / ethanol / 8 h / Heating
View Scheme
参考文献
Soni, Namita; Barthwal, J. P.; Gupta, T. K.; Bhalla, T. N.; Parmar, S. S.; Bhargava, K. P.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. <B> 22, # 8 p. 785 - 788
反应条件
1: 80percent hydrazine hydrate / 2 h / Heating
2: ethanol / 6 h / Heating
View Scheme
参考文献
Dehuri, S. N.; Pradhan, P. C.; Nayak, A.
Journal of the Indian Chemical Society, 1983 , vol. 60, p. 475 - 478
反应条件
1: 80percent hydrazine hydrate / 2 h / Heating
2: ethanol / 6 h / Heating
3: aq. NaOH / ethanol / 4 h / Heating
View Scheme
参考文献
Dehuri, S. N.; Pradhan, P. C.; Nayak, A.
Journal of the Indian Chemical Society, 1983 , vol. 60, p. 475 - 478
反应条件
1: 65 percent / NaOH / H2O / Heating
2: 70 percent / Ac2O, Py
3: 40 percent / NaOAc / ethanol / 8 h / Heating
View Scheme
参考文献
Soni, Namita; Barthwal, J. P.; Gupta, T. K.; Bhalla, T. N.; Parmar, S. S.; Bhargava, K. P.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. <B> 22, # 8 p. 785 - 788
反应条件
1: 65 percent / NaOH / H2O / Heating
2: 70 percent / Ac2O, Py
3: 55 percent / NaOAc / ethanol / 8 h / Heating
View Scheme
参考文献
Soni, Namita; Barthwal, J. P.; Gupta, T. K.; Bhalla, T. N.; Parmar, S. S.; Bhargava, K. P.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. <B> 22, # 8 p. 785 - 788
反应条件
1: 65 percent / NaOH / H2O / Heating
2: 70 percent / Ac2O, Py
3: 50 percent / NaOAc / ethanol / 8 h / Heating
View Scheme
参考文献
Soni, Namita; Barthwal, J. P.; Gupta, T. K.; Bhalla, T. N.; Parmar, S. S.; Bhargava, K. P.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. <B> 22, # 8 p. 785 - 788
反应条件
1: KOH / dimethylformamide
2: Fe, NH4Cl / tetrahydrofuran; H2O
View Scheme
参考文献
Jin, Byung-Woo; Cho, Sung-Hye
Heterocycles, 1994 , vol. 38, # 6 p. 1213 - 1216
反应条件
potassium hydroxide in ethanol
T=50 - 60°C;
参考文献
Bourdais; Dauvillier; Gayral; et al.
European Journal of Medicinal Chemistry, 1981 , vol. 16, # 3 p. 233 - 239
反应条件
potassium hydroxide in propan-1-ol; water
18 h; Heating;
参考文献
Agrawal, V. K.; Rao, K. V. B.; Sharma, Satyavan
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1983 , vol. <B> 22, # 8 p. 781 - 784