S-(+)-1,1’-联萘-2’-甲氧基-2-二苯膦合成路线 （共 12 条）
反应条件
potassium carbonate in acetone
3 h; Heating;
参考文献
Uozumi, Yasuhiro; Hayashi, Tamio
Journal of the American Chemical Society, 1991 , vol. 113, # 26 p. 9887 - 9888
反应条件
1: 99 percent / 3N aq. NaOH / methanol; dioxane / 12 h / Ambient temperature
2: 99 percent / K2CO3 / acetone / 3 h / Heating
View Scheme
参考文献
Uozumi, Yasuhiro; Tanahashi, Asako; Lee, Sang-Yong; Hayashi, Tamio
Journal of Organic Chemistry, 1993 , vol. 58, # 7 p. 1945 - 1948
反应条件
1: 95 percent / diisopropylethylamine / palladium diacetate, 1,4-bis(diphenylphosphino)butane / dimethylsulfoxide / 12 h / 100 °C
2: 99 percent / 3N aq. NaOH / methanol; dioxane / 12 h / Ambient temperature
3: 99 percent / K2CO3 / acetone / 3 h / Heating
View Scheme
参考文献
Uozumi, Yasuhiro; Tanahashi, Asako; Lee, Sang-Yong; Hayashi, Tamio
Journal of Organic Chemistry, 1993 , vol. 58, # 7 p. 1945 - 1948
反应条件
1: 95 percent / diisopropylethylamine / palladium diacetate, 1,4-bis(diphenylphosphino)butane / dimethylsulfoxide / 12 h / 100 °C
2: 99 percent / 3N aq. NaOH / methanol; dioxane / 12 h / Ambient temperature
3: 99 percent / K2CO3 / acetone / 3 h / Heating
View Scheme
参考文献
Uozumi, Yasuhiro; Tanahashi, Asako; Lee, Sang-Yong; Hayashi, Tamio
Journal of Organic Chemistry, 1993 , vol. 58, # 7 p. 1945 - 1948
反应条件
1: 100 percent / pyridine / CH2Cl2 / 6 h / 0 °C
2: 95 percent / diisopropylethylamine / palladium diacetate, 1,4-bis(diphenylphosphino)butane / dimethylsulfoxide / 12 h / 100 °C
3: 99 percent / 3N aq. NaOH / methanol; dioxane / 12 h / Ambient temperature
4: 99 percent / K2CO3 / acetone / 3 h / Heating
View Scheme
参考文献
Uozumi, Yasuhiro; Tanahashi, Asako; Lee, Sang-Yong; Hayashi, Tamio
Journal of Organic Chemistry, 1993 , vol. 58, # 7 p. 1945 - 1948
反应条件
in tetrahydrofuran; benzene
18 h; Heating;
参考文献
Hattori; Sakamoto; Hayashizaka; Miyano
Synthesis, 1994 , # 2 p. 199 - 202
反应条件
1: 1.) BuLi, TMEDA, 2.) 30percent H2O2 aq., AcOH / 1.) Et2O, hexane, r.t., 2 h, 2.) r.t. to 70 deg C, 0.5 h
2: 59 percent / tetrahydrofuran; benzene / 18 h / Heating
View Scheme
参考文献
Hattori; Sakamoto; Hayashizaka; Miyano
Synthesis, 1994 , # 2 p. 199 - 202
反应条件
1: 1.) BuLi, TMEDA, 2.) 30percent H2O2 aq., AcOH / 1.) Et2O, hexane, r.t., 2 h, 2.) r.t. to 70 deg C, 0.5 h
2: 59 percent / tetrahydrofuran; benzene / 18 h / Heating
View Scheme
参考文献
Hattori; Sakamoto; Hayashizaka; Miyano
Synthesis, 1994 , # 2 p. 199 - 202
反应条件
1: aq. NaN3 / acetone / 0.25 h / Ambient temperature
2: H2O / tetrahydrofuran / 1 h / Heating
3: 1.) NaNO2, H2SO4, 2.) KI, H2SO4 / 1.) H2O, 0 deg C, 30 min, 2.) H2O, 4 deg C
4: 1.) Mg, 1,2-dibromoethane / 1.) THF, reflux, irradiation, 2 h, 2.) THF, benzene, RT, overnight
5: 30percent H2O2, AcOH / 2 h / 70 °C
View Scheme
参考文献
Hattori, Tetsutaro; Shijo, Masayuki; Sakamoto, Jun'ichi; Kumagai, Satoshi; Nakajima, Akihiko; Miyano, Sotaro
Journal of Chemical Research, Miniprint, 1995 , # 1 p. 124 - 134
反应条件
1: SOCl2 / 3 h / Heating
2: aq. NaN3 / acetone / 0.25 h / Ambient temperature
3: H2O / tetrahydrofuran / 1 h / Heating
4: 1.) NaNO2, H2SO4, 2.) KI, H2SO4 / 1.) H2O, 0 deg C, 30 min, 2.) H2O, 4 deg C
5: 1.) Mg, 1,2-dibromoethane / 1.) THF, reflux, irradiation, 2 h, 2.) THF, benzene, RT, overnight
6: 30percent H2O2, AcOH / 2 h / 70 °C
View Scheme
参考文献
Hattori, Tetsutaro; Shijo, Masayuki; Sakamoto, Jun'ichi; Kumagai, Satoshi; Nakajima, Akihiko; Miyano, Sotaro
Journal of Chemical Research, Miniprint, 1995 , # 1 p. 124 - 134
