1: 91 percent / tBuOOH, Ti(OiPr)4, (-)-diethyl tartrate ((-)-DET), 4-A sieves / CH2Cl2 / -20 °C 2: Ti(OiPr)4, Me3SiN3 / benzene 3: 91 percent / NEt3, 4-dimethylaminopyridine (DMAP) / CH2Cl2 4: (CH3)3SiOTf / 1,2-dichloro-ethane 5: NaOH / methanol 6: 4.7 N H2SO4 / methanol View Scheme

1: diisopropylethylamine 2: K2OsO4*2H2O, K3Fe(CN)6, DHQD-PHN / H2O; 2-methyl-propan-2-ol 3: H2SO4 / tetrahydrofuran / 0 °C 4: 80 percent / NaH / dimethylformamide 5: 84 percent / Rh(PPh3)3Cl, pyridine / aq. ethanol / 5 h / Heating 6: 28 percent / pyridine*HF / dioxane 7: 86 percent / 50percent TFA / CH2Cl2 View Scheme