(4-氯苯甲酰基氨基)-乙酸合成路线 （共 16 条）
反应条件
potassium hydroxide in ethanol T=20°C; 0.5 h;
参考文献
Pessoa-Mahana, Hernan; Astudillo, Claudio I. O.; Araya-Maturana
Synthetic Communications, 2002 , vol. 32, # 9 p. 1437 - 1445
参考文献
Journal of Biological Chemistry, , vol. 67, p. 557
反应条件
sodium hydroxide T=20°C; 2 h;
参考文献
Oelschlaeger; Seeling; Radman; Bockhard
Die Pharmazie, 2000 , vol. 55, # 11 p. 825 - 828
反应条件
1: (COCl)2, DMF / benzene / Ambient temperature 2: NaOH / H2O / 70 - 80 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 32, # 5 p. 1033 - 1038
反应条件
1: 82 percent / tetrahydrofuran / 3 h / 0 - 20 °C 2: 87 percent / KOH / ethanol / 0.5 h / 20 °C View Scheme
参考文献
Synthetic Communications, , vol. 32, # 9 p. 1437 - 1445
反应条件
hydroxide T=25°C; kinetic parameters for hydrolysis, pH dependence; Rate constant;
参考文献
Journal of the American Chemical Society, , vol. 102, # 22 p. 6828 - 6837
反应条件
acetic anhydride 1 h; Heating;
参考文献
El-Hashash, M. A.; Afify, A. A.; Kaddah, A. M.; El-Kady, S. S.
Synthesis, 1981 , # 10 p. 798 - 801
参考文献
Crawford; Little
Journal of the Chemical Society, 1959 , p. 729
反应条件
sodium acetate; acetic anhydride T=100°C;
参考文献
Perni, Robert B.; Conway, Samuel C.; Ladner, Stephanie K.; Zaifert, Katie; Otto, Michael J.; King, Robert W.
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 23 p. 2687 - 2690
参考文献
Crawford; Little
Journal of the Chemical Society, 1959 , p. 729
