(R)-2-甲酰基-1-哌啶甲酸叔丁酯合成路线 (共 14 条)
反应条件
1: palladium 10 on activated carbon; hydrogen / ethyl acetate / 6 h / 20 °C 2: methanol; toluene-4-sulfonic acid / 5 h / 20 °C 3: sodium periodate; sodium hydrogencarbonate / dichloromethane; water / 1 h / 20 °C View Scheme
参考文献
Tetrahedron, , vol. 67, # 6 p. 1341 - 1347
反应条件
1: methanol; toluene-4-sulfonic acid / 5 h / 20 °C 2: sodium periodate; sodium hydrogencarbonate / dichloromethane; water / 1 h / 20 °C View Scheme
参考文献
Tetrahedron, , vol. 67, # 6 p. 1341 - 1347
反应条件
sodium tetrahydroborate in ethanol T=20°C; 1 h;
参考文献
Schuetzenmeister, Nina; Mueller, Michael; Reinscheid, Uwe M.; Griesinger, Christian; Leonov, Andrei
Chemistry - A European Journal, 2013 , vol. 19, # 51 p. 17584 - 17588
反应条件
1.1: benzene / 6 h / 50 °C 2.1: AD-mix-βreg;; methanesulfonamide / water; #tert!-butyl alcohol / 24 h / 0 °C 3.1: trifluoroacetic acid / 10 h 3.2: 6 h / Reflux View Scheme
参考文献
Kamal, Ahmed; Vangala, Saidi Reddy
Tetrahedron, 2011 , vol. 67, # 6 p. 1341 - 1347