3-氮杂双环[3.1.0]-6-己基氨基甲酸叔丁酯合成路线 （共 12 条）
反应条件
hydrogen; palladium dihydroxide in methanol 48 h;
参考文献
Sun, Qin; Zhu, Ran; Foss Jr., Frank W.; Macdonald, Timothy L.
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 24 p. 6682 - 6686
反应条件
hydrogen; palladium on activated charcoal in methanol T=0°C; 5 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 11 p. 2773 - 2776
反应条件
1: LiAlH4 / tetrahydrofuran / 48 h / Heating 2: H2 / Pd/C / methanol / 23 h / 0 °C 3: aq. K2CO3 / dioxane / 15 h / 20 °C 4: CrO3; aq. H2SO4 / acetone / 2 h / 0 - 20 °C 5: NEt3; (PhO)2P(O)N3 / 44 h / Heating 6: H2 / Pd/C / methanol / 5 h / 0 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 11 p. 2773 - 2776
反应条件
1: NEt3; (PhO)2P(O)N3 / 44 h / Heating 2: H2 / Pd/C / methanol / 5 h / 0 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 11 p. 2773 - 2776
反应条件
1: aq. K2CO3 / dioxane / 15 h / 20 °C 2: CrO3; aq. H2SO4 / acetone / 2 h / 0 - 20 °C 3: NEt3; (PhO)2P(O)N3 / 44 h / Heating 4: H2 / Pd/C / methanol / 5 h / 0 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 11 p. 2773 - 2776
反应条件
1: H2 / Pd/C / methanol / 23 h / 0 °C 2: aq. K2CO3 / dioxane / 15 h / 20 °C 3: CrO3; aq. H2SO4 / acetone / 2 h / 0 - 20 °C 4: NEt3; (PhO)2P(O)N3 / 44 h / Heating 5: H2 / Pd/C / methanol / 5 h / 0 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 11 p. 2773 - 2776
反应条件
1: CrO3; aq. H2SO4 / acetone / 2 h / 0 - 20 °C 2: NEt3; (PhO)2P(O)N3 / 44 h / Heating 3: H2 / Pd/C / methanol / 5 h / 0 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 11 p. 2773 - 2776
反应条件
1: Na2CO3; aq. NaOH / ethyl acetate / 3 h / 30 °C 2: 89 percent / H2O; H2 / 10percent Pd/C / methanol / 20 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1, , # 10 p. 1615 - 1622
反应条件
1: H2; H2O / 5percent Pt/C / methanol / 24 h / 50 °C / 2660.18 Torr 2: Na2CO3; aq. NaOH / ethyl acetate / 3 h / 30 °C 3: 89 percent / H2O; H2 / 10percent Pd/C / methanol / 20 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1, , # 10 p. 1615 - 1622
反应条件
1: 97 percent / NaBH4; BF3*THF / tetrahydrofuran / 3 h / 40 °C 2: H2; H2O / 5percent Pt/C / methanol / 24 h / 50 °C / 2660.18 Torr 3: Na2CO3; aq. NaOH / ethyl acetate / 3 h / 30 °C 4: 89 percent / H2O; H2 / 10percent Pd/C / methanol / 20 °C View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1, , # 10 p. 1615 - 1622
