(2-甲基-1,3-噻唑-4-基)乙腈合成路线 （共 10 条）
反应条件
in ethanol; water; sodium hydrogencarbonate; ethyl acetate
参考文献
US6194437 B1, ;
US 6194437 B1
反应条件
1: thionyl chloride; pyridine / CH2Cl2 / 2 h / -30 - 20 °C 2: 0.21 g / dimethylsulfoxide View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 14, # 9 p. 3185 - 3198
反应条件
1: 65 percent / LiBH4 / ethanol; tetrahydrofuran / 0 - 20 °C 2: thionyl chloride; pyridine / CH2Cl2 / 2 h / -30 - 20 °C 3: 0.21 g / dimethylsulfoxide View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 14, # 9 p. 3185 - 3198
参考文献
Journal of Organic Chemistry, , vol. 12, p. 342,351
反应条件
1: aqueous NH3 2: POCl3 View Scheme
参考文献
Journal of Organic Chemistry, , vol. 12, p. 342,351
反应条件
in dimethyl sulfoxide
参考文献
Bioorganic and Medicinal Chemistry, , vol. 14, # 9 p. 3185 - 3198
反应条件
ammonia; nickel T=110 - 130°C; P=55163.1 Torr; Hydrogenation;
参考文献
Burger; Ullyot
Journal of Organic Chemistry, 1947 , vol. 12, p. 342,351
反应条件
hydrogenchloride; zinc(II) chloride in diethyl ether; trifluoroacetic acid
参考文献
Pivovarenko, V. G.; Khilya, V. P.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1991 , vol. 27, # 5 p. 496 - 501
Khimiya Geterotsiklicheskikh Soedinenii, 1991 , vol. 27, # 5 p. 625 - 631
反应条件
hydrogenchloride; boron trifluoride diethyl etherate
参考文献
Khilya,V.P. et al.
Journal of Organic Chemistry USSR (English Translation), 1973 , vol. 9, p. 2580 - 2586
Zhurnal Organicheskoi Khimii, 1973 , vol. 9, p. 2561 - 2567
反应条件
1: HCl, BF3-Et2O
2: Et3N
3: aq. NaOH / ethanol
View Scheme
参考文献
Khilya,V.P. et al.
Journal of Organic Chemistry USSR (English Translation), 1973 , vol. 9, p. 2580 - 2586
Zhurnal Organicheskoi Khimii, 1973 , vol. 9, p. 2561 - 2567
