1: With water; lithium hydroxide hydrate in tetrahydrofuran T=20°C; 0.5 h; 2: With hydrogenchloride pH=5; Cooling with ice;
参考文献
DECIPHERA PHARMACEUTICALS, LLC; FLYNN, Daniel L.; KAUFMAN, Michael D.
Patent: WO2011/137342 A1, 2011 ;
Location in patent: Page/Page column 34 ;
WO 2011/137342 A1
