(S)-3-溴-alpha-甲基苄醇合成路线 （共 16 条）
反应条件
chiral Cr(Salen)complex catalyst in toluene T=20°C; 24 h;
参考文献
Cozzi, Pier Giorgio; Kotrusz, Peter
Journal of the American Chemical Society, 2006 , vol. 128, # 15 p. 4940 - 4941
反应条件
di-μ-chloro-bis(η4-1,5-cyclooctadiene)diiridium; C45H58NP; potassium tert-butylate; hydrogen in propan-1-ol T=25 - 30°C; P=4560.31 Torr; 0.166667 h; Autoclave; optical yield given as percent eeenantioselective reaction;
参考文献
Xie, Jian-Bo; Xie, Jian-Hua; Liu, Xiao-Yan; Zhang, Qian-Qian; Zhou, Qi-Lin
Chemistry - An Asian Journal, 2011 , vol. 6, # 3 p. 899 - 908
反应条件
benzo[1,3,2]dioxaborole; chiral catalyst 1a in hexane T=-30°C; 1 h; different titanium alkoxide catalysts, other solvents and reaction time; also reduction of further ketones; Product distribution;
参考文献
Angewandte Chemie, , vol. 107, # 18 p. 2165 - 2166
反应条件
Arthrobacter atrocyaneus in N,N-dimethyl-formamide T=32°C; 72 h; Microbiological reaction; enantioselective reaction;
参考文献
Silva, Camila R.; Souza, Juliana C.; Araujo, Lidiane S.; Kagohara, Edna; Garcia, Thais P.; Pelizzari, Vivian H.; Andrade, Leandro H.
Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 83, p. 23 - 28
反应条件
N-ethyl-N,N-diisopropylamine; CF3-PIP in chloroform T=0°C; 8.25 h; Resolution of racemate; Product distribution / selectivity;
参考文献
US2005/256150 A1, ;
Page/Page column 18 ;
反应条件
(S)-(N-(ferrocenylmethyl)azetidin-2-yl)(diphenyl)methanol in toluene T=30°C; 48 h; Title compound not separated from byproducts.;
参考文献
Journal of Organic Chemistry, , vol. 73, # 1 p. 168 - 176
反应条件
1: 75 percent / trichlorosilane; [(R)-1,1'-spirobiindane-7,7'-dioxy][((R)-PhMeCH)2N]phosphane / [Pd(η3-allyl)Cl]2 / 45 h / 15 - 20 °C 2: H2O2; KF; KHCO3 / methanol; tetrahydrofuran View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 15, # 14 p. 2231 - 2234
反应条件
(R)-5-CF3-2-Ph-2,3-dihydroimidazo[1,2-a]pyridine; N-ethyl-N,N-diisopropylamine in chloroform 8 h; cooling; Title compound not separated from byproducts;
参考文献
Journal of the American Chemical Society, , vol. 126, # 39 p. 12226 - 12227
反应条件
titanium(IV) isopropylate; 1-((S)-2-((R)-hydroxy(naphthalen-2-yl)methyl)naphthalen-1-yl)naphthalen-2-ol in toluene T=-40°C; Schlenk technique; Overall yield = 94 percent; enantioselective reaction;
参考文献
European Journal of Organic Chemistry, , # 4 p. 748 - 750
反应条件
phosphate buffer in 1,4-dioxane T=25°C; pH=8.0; 50 h;
参考文献
Tetrahedron Asymmetry, , vol. 19, # 5 p. 549 - 553
