反应条件
1: 4-chloro-7-(phenylsulfonyl)-7H-pyrrolo[2,3-d]pyrimidine With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 4 h; Inert atmosphere; 2: carbon dioxide in tetrahydrofuran; hexane T=-78 - 20°C; Inert atmosphere; 3: With hydrogenchloride in water Inert atmosphere;
参考文献
Beckers, Thomas; Sellmer, Andreas; Eichhorn, Emerich; Pongratz, Herwig; Schaechtele, Christoph; Totzke, Frank; Kelter, Gerhard; Krumbach, Rebekka; Fiebig, Heinz-Herbert; Boehmer, Frank-D.; Mahboobi, Siavosh
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 1 p. 125 - 136
