sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in ethylene glycol dimethyl ether; water T=140°C; Suzuki Coupling; 0.166667 h; Inert atmosphereMicrowave irradiationSealed vial;

1: 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4-methyl-morpholine / dimethyl sulfoxide / 32 h / 20 °C / Inert atmosphere; Sealed tube 2: isopropylamine / n-heptane; ethanol / 20 °C / Resolution of racemate 3: sodium carbonate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct / ethylene glycol dimethyl ether; water / 0.17 h / 140 °C / Inert atmosphere; Microwave irradiation; Sealed vial View Scheme

1: isopropylamine / n-heptane; ethanol / 20 °C / Resolution of racemate 2: sodium carbonate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct / ethylene glycol dimethyl ether; water / 0.17 h / 140 °C / Inert atmosphere; Microwave irradiation; Sealed vial View Scheme

1: 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; 4-methyl-morpholine / dimethyl sulfoxide / 32 h / 20 °C / Inert atmosphere; Sealed tube 2: isopropylamine / n-heptane; ethanol / 20 °C / Resolution of racemate 3: sodium carbonate / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct / ethylene glycol dimethyl ether; water / 0.17 h / 140 °C / Inert atmosphere; Microwave irradiation; Sealed vial View Scheme