5-苯基戊-2,4-二烯醛合成路线 （共 14 条）
反应条件
1.1: n-butyllithium / tetrahydrofuran / 0.02 h / -78 °C / Inert atmosphere
1.2: Inert atmosphere
2.1: sulfuric acid; silica gel / dichloromethane; water / 0.5 h
3.1: tetrahydrofuran / -78 - 20 °C / Inert atmosphere
4.1: manganese(IV) oxide / dichloromethane / 1 h
View Scheme
参考文献
Dabdoub, Miguel J.; Dabdoub, Vania B.; Baroni, Adriano C.M.; Barbosa, Sandro L.
Synthetic Communications, 2012 , vol. 42, # 7 p. 942 - 950
反应条件
(i) Mg, EtBr, (ii) /BRN= 1904954/; Multistep reaction;
参考文献
Mikhailov,B.M.; Ter-Sarkisyan,G.S.
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1960 , p. 1175 - 1178
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1960 , # 7 p. 1267 - 1271
反应条件
lithium methanolate in methanol
参考文献
Leznoff,C.C.; Hayward,R.J.
Canadian Journal of Chemistry, 1972 , vol. 50, p. 528 - 533
反应条件
hydrogen; KOC(O)Ph; C44H39NOP2Rh(1+)*Cl(1-) in dichloromethane
T=25°C; P=15001.5 - 18751.9 Torr; 1 h; Inert atmosphere; Product distribution / selectivity;
参考文献
FIRMENICH SA; SAUDAN, Michel, Alfred, Joseph; SAUDAN, Sylvia, Joyeuse, Adelaide, Ada; SAUDAN, Lionel
Patent: WO2012/150053 A1, 2012 ;
Location in patent: Page/Page column 21-23 ;
