(2R,3S,4S,5R)-2-(4-氨基-2-氧代嘧啶-1-基)-4-羟基-5-(羟基甲基)四氢呋喃-3-甲腈盐酸盐合成路线 （共 2 条）
反应条件
Tris-HCl buffer T=37°C; 6 h; var. salt concentration and pH of buffer; Rate constantMechanism;
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 17 p. 3391 - 3397
反应条件
1: With triethylamine in methanol; dichloromethane T=15 - 30°C; pH=9 - 9.5; 2: With acetic acid T=30°C; pH=4.0 - 4.5;
参考文献
CYCLACEL LIMITED
Patent: WO2009/136162 A1, 2009 ;
Location in patent: Page/Page column 19 ;
