hydrogenchloride T=100°C; 2.5 h;

1: 81 percent / 4.5 N HCl / 2.5 h / 100 °C 2: 100 percent / HCl gas / 0 - 5 °C View Scheme

1: 81 percent / 4.5 N HCl / 2.5 h / 100 °C 2: 100 percent / HCl gas / 0 - 5 °C 3: 84 percent / triethylamine, DCC / tetrahydrofuran / Ambient temperature 4: 67 percent / trifluoroacetic acid / CH2Cl2 / 0.67 h / 0 °C 5: 75 percent / DCC / CH2Cl2 / 1.) -20 deg C to 0 deg C, 3 h, 2.) 4 deg C, 36 h 6: ethanethiol, AlBr3 / CH2Cl2 / 24 h / Ambient temperature 7: DCC, DMAP, DMAP-TFA / CHCl3 / 16 h / Heating View Scheme