5,7-二氯噻唑并[5,4-d]嘧啶合成路线 (共 3 条)
反应条件
N-ethyl-N,N-diisopropylamine; trichlorophosphate 30 h; RefluxInert atmosphere;
参考文献
Shu, Lianhe; Alabanza, Lady Mae; Gu, Chen
Heterocycles, 2012 , vol. 85, # 7 p. 1721 - 1726
反应条件
1: ammonium hydroxide / ethanol; water / 40 °C / Reflux 2: potassium tert-butylate / N,N-dimethyl acetamide / 1 h / 100 °C / Inert atmosphere 3: N-ethyl-N,N-diisopropylamine; trichlorophosphate / 30 h / Reflux; Inert atmosphere View Scheme
参考文献
Heterocycles, , vol. 85, # 7 p. 1721 - 1726
反应条件
1: potassium tert-butylate / N,N-dimethyl acetamide / 1 h / 100 °C / Inert atmosphere 2: N-ethyl-N,N-diisopropylamine; trichlorophosphate / 30 h / Reflux; Inert atmosphere View Scheme
参考文献
Heterocycles, , vol. 85, # 7 p. 1721 - 1726