(4-碘苯基乙炔)三甲基硅烷合成路线 （共 30 条）
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine in tetrahydrofuran
T=25°C; Sonogashira coupling reaction;
参考文献
Zhi, Yong-Gang; Lai, Siu-Wai; Chan, Queenie K.-W.; Law, Yuen-Chi; Tong, Glenna S.-M.; Che, Chi-Ming
European Journal of Organic Chemistry, 2006 , # 14 p. 3125 - 3139
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine in tetrahydrofuran
T=25°C; Sonogashira coupling reaction;
参考文献
Zhi, Yong-Gang; Lai, Siu-Wai; Chan, Queenie K.-W.; Law, Yuen-Chi; Tong, Glenna S.-M.; Che, Chi-Ming
European Journal of Organic Chemistry, 2006 , # 14 p. 3125 - 3139
反应条件
1: [Pd2(dba)3*CHCl3]; PPh3; Et3N / CuI / 20 °C
2: NaOH; water / ethanol; tetrahydrofuran / 1 h / 20 °C
3: [Pd2(dba)3*CHCl3]; PPh3; Et3N / CuI / 20 °C
4: Bu4NF / tetrahydrofuran / 2 h / 20 °C
View Scheme
参考文献
Ljungdahl, Thomas; Pettersson, Karin; Albinsson, Bo; Martensson, Jerker
European Journal of Organic Chemistry, 2006 , # 14 p. 3087 - 3096
反应条件
1: trimethyl[4-(4-(phenylethynyl)phenylethynyl)phenylethynyl]silane With potassium hydroxide in tetrahydrofuran; methanol
T=25°C;
2: 4-(TMS-ethynyl)iodobenzene With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine in tetrahydrofuran
T=25°C; Sonogashira coupling reaction;
参考文献
Zhi, Yong-Gang; Lai, Siu-Wai; Chan, Queenie K.-W.; Law, Yuen-Chi; Tong, Glenna S.-M.; Che, Chi-Ming
European Journal of Organic Chemistry, 2006 , # 14 p. 3125 - 3139
反应条件
1.1: KOH / methanol; tetrahydrofuran / 25 °C
1.2: Pd(PPh3)2Cl2; CuI; NHEt2 / tetrahydrofuran / 25 °C
2.1: KOH / methanol; tetrahydrofuran / 25 °C
2.2: Pd(PPh3)2Cl2; CuI; NHEt2 / tetrahydrofuran / 25 °C
View Scheme
参考文献
Zhi, Yong-Gang; Lai, Siu-Wai; Chan, Queenie K.-W.; Law, Yuen-Chi; Tong, Glenna S.-M.; Che, Chi-Ming
European Journal of Organic Chemistry, 2006 , # 14 p. 3125 - 3139
反应条件
1: With n-butyllithium in tetrahydrofuran; hexane
T=-78°C; 0.25 h;
2: With boric acid trimethyl ester in tetrahydrofuran
T=25°C; 0.5 h;
参考文献
Wan, Chi-Wai; Burghart, Armin; Chen, Jiong; Bergstroem, Fredrik; Johansson, Lennart B.-A.; Wolford, Matthew F.; Kim, Taeg Gyum; Topp, Michael R.; Hochstrasser, Robin M.; Burgess, Kevin
Chemistry - A European Journal, 2003 , vol. 9, # 18 p. 4430 - 4441
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; N-ethyl-N,N-diisopropylamine in tetrahydrofuran
T=20°C; Sonogashira coupling; 24 h;
参考文献
Hwang, Jiunn-Jye; Tour, James M.
Tetrahedron, 2002 , vol. 58, # 52 p. 10387 - 10405
反应条件
1: 1-(phenylethynyl)-4-[(trimethylsilyl)ethynyl]benzene With potassium hydroxide in tetrahydrofuran; methanol
T=25°C;
2: 4-(TMS-ethynyl)iodobenzene With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine in tetrahydrofuran
T=25°C; Sonogashira coupling reaction;
参考文献
Zhi, Yong-Gang; Lai, Siu-Wai; Chan, Queenie K.-W.; Law, Yuen-Chi; Tong, Glenna S.-M.; Che, Chi-Ming
European Journal of Organic Chemistry, 2006 , # 14 p. 3125 - 3139
反应条件
1.1: KOH / methanol; tetrahydrofuran / 25 °C
1.2: Pd(PPh3)2Cl2; CuI; NHEt2 / tetrahydrofuran / 25 °C
2.1: KOH / methanol; tetrahydrofuran / 25 °C
2.2: Pd(PPh3)2Cl2; CuI; NHEt2 / tetrahydrofuran / 25 °C
View Scheme
参考文献
Zhi, Yong-Gang; Lai, Siu-Wai; Chan, Queenie K.-W.; Law, Yuen-Chi; Tong, Glenna S.-M.; Che, Chi-Ming
European Journal of Organic Chemistry, 2006 , # 14 p. 3125 - 3139
参考文献
Hwang, Jiunn-Jye; Tour, James M.
Tetrahedron, 2002 , vol. 58, # 52 p. 10387 - 10405
