顺-7,10,13,16二十二碳四烯酸甲酯合成路线 （共 8 条）
反应条件
1: With potassium hydroxide; water in methanol T=55°C; 1.5 h; 2: methanol With sulfuric acid in water T=20 - 55°C; 1.5 h; Product distribution / selectivity;
参考文献
WO2008/86495 A1, ;
Page/Page column 18; 21-22; 29 ;
反应条件
1: (i) EtMgBr, THF, (ii) CuCN, (iii) /BRN= 1926282/ 2: (i) H2, quinoline, Pd-CaCO3, pentyl acetate, (ii) /BRN= 1098229/, aq. HCl View Scheme
参考文献
Hoppe-Seyler's Zeitschrift fuer physiologische Chemie, , vol. 352, # 4 p. 542 - 548
反应条件
1: (i) EtMgBr, THF, (ii) CuCN, (iii) /BRN= 1926282/ 2: (i) H2, quinoline, Pd-CaCO3, pentyl acetate, (ii) /BRN= 1098229/, aq. HCl View Scheme
参考文献
Hoppe-Seyler's Zeitschrift fuer physiologische Chemie, , vol. 352, # 4 p. 542 - 548
反应条件
1: (i) EtMgBr, THF, (ii) CuCN, (iii) /BRN= 1768816/ 2: (i) H2, quinoline, Lindlar catalyst, PE, (ii) /BRN= 102415/ View Scheme
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 85, p. 1233 - 1250
反应条件
1: (i) EtMgBr, THF, (ii) CuCN, (iii) /BRN= 1768816/ 2: (i) H2, quinoline, Lindlar catalyst, PE, (ii) /BRN= 102415/ View Scheme
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 85, p. 1233 - 1250
反应条件
(i) H2, quinoline, Lindlar catalyst, PE, (ii) /BRN= 102415/; Multistep reaction;
参考文献
Recueil des Travaux Chimiques des Pays-Bas, , vol. 85, p. 1233 - 1250
反应条件
(i) H2, quinoline, Pd-CaCO3, pentyl acetate, (ii) /BRN= 1098229/, aq. HCl; Multistep reaction;
参考文献
Hoppe-Seyler's Zeitschrift fuer physiologische Chemie, , vol. 352, # 4 p. 542 - 548
反应条件
T=55°C; 1.5 h; Product distribution / selectivity;
参考文献
WO2008/86495 A1, ;
Page/Page column 18; 21-22; 29 ;
