4-氨基-n-羟基-1,2,5-噁二唑-3-羧酰胺合成路线 （共 14 条）
反应条件
(i) aq. NaNO2, HCl, (ii) NH2OH*HCl, aq. NaOH; Multistep reaction;
参考文献
Journal of Heterocyclic Chemistry, , vol. 2, p. 253 - 255
反应条件
sodium hydroxide Heating;
参考文献
Journal of Heterocyclic Chemistry, , vol. 2, p. 253 - 255
参考文献
Gazzetta Chimica Italiana, , vol. 61, p. 561,571
Gazzetta Chimica Italiana, , vol. 66, p. 127,133
参考文献
Russian Chemical Bulletin, , vol. 43, # 3 p. 402 - 404
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , # 3 p. 444 - 446
反应条件
morpholine other base; MechanismProduct distribution;
参考文献
Chemistry of Heterocyclic Compounds (New York, NY, United States), , p. 707
Khimiya Geterotsiklicheskikh Soedinenii, , vol. 24, # 6 p. 856 - 857
反应条件
hydrogenchloride; acetic acid; sodium chloride; sodium nitrite in water T=0 - 15°C; 4 h;
参考文献
THE UNIVERSITY OF CHICAGO; GAJEWSKI, Thomas F.; SPRANGER, Stefani; LEUNG, Michael
Patent: WO2014/66834 A1, 2014 ;
Location in patent: Paragraph 00185 ;
反应条件
sulfuric acid; bromine T=0 - 5°C;
参考文献
Andrianov, B. G.; Eremeev, A. V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1994 , vol. 30, # 3 p. 370 - 371
Khimiya Geterotsiklicheskikh Soedinenii, 1994 , # 3 p. 420 - 421
反应条件
lead dioxide; acetic acid 1.5 h; Ambient temperature;
参考文献
Andrianov, V. G.; Eremeev, A. V.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1994 , vol. 30, # 5 p. 608 - 611
Khimiya Geterotsiklicheskikh Soedinenii, 1994 , # 5 p. 693 - 696
参考文献
Ichikawa,T. et al.
Journal of Heterocyclic Chemistry, 1965 , vol. 2, p. 253 - 255
参考文献
Ichikawa,T. et al.
Journal of Heterocyclic Chemistry, 1965 , vol. 2, p. 253 - 255
