palladium 10 on activated carbon; hydrogen in ethanol T=70°C; P=52505.3 Torr; Continuous-flow conditions;

1: palladium 10 on activated carbon; hydrogen / ethanol / 70 °C / 52505.3 Torr / Continuous-flow conditions 2: triethylamine / methanol / 3 h / Reflux View Scheme

<b>Multi-step reaction with 3 steps<br /> </b>1.1: potassium carbonate / water / 20 &deg;C<br />2.1: sodium hydride / tetrahydrofuran; mineral oil / 2 h / Reflux<br />2.2: 17 h / 0 - 20 &deg;C<br />3.1: sodium tetrahydroborate / tetrahydrofuran; methanol / 1.5 h / Reflux<br />3.2: 20 &deg;C<br /> <br /> &nbsp;