[2S-[1(S*),2alpha,4beta]]-4-甲基-1-(1-苯基乙基)-2-哌啶羧酸乙酯合成路线 （共 5 条）
反应条件
hydrogen; palladium hydroxide - carbon in ethanol
P=760 Torr; Ambient temperature;
参考文献
Bailey, Patrick D.; Brown, George R.; Korber, Fritjof; Reed, Amanda; Wilson, Robert D.
Tetrahedron: Asymmetry, 1991 , vol. 2, # 12 p. 1263 - 1282
反应条件
<b>With</b> <a href="#" onclick="return RXDsubstances(event, this, '3587189', constants.ctx, '0')">hydrogen</a>; <a href="#" onclick="return RXDsubstances(event, this, '11465123', constants.ctx, '0')">platinum on activated charcoal</a> <b>in</b> <a href="#" onclick="return RXDsubstances(event, this, '506104', constants.ctx, '0')">ethyl acetate</a> <br />P=760 Torr; 16 h; Ambient temperature; Yield given. Yields of byproduct given; <br />
参考文献
Bailey, Patrick D.; Wilson, Robert D.; Brown, George R. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 5 p. 1337 - 1340
反应条件
<b>Multi-step reaction with 2 steps<br /> </b>1: trifluoroacetic acid (TFA), H<sub>2</sub>O / dimethylformamide / 30 h / Ambient temperature<br />2: H<sub>2</sub> / 3percent Pt/C / ethyl acetate / 16 h / 760 Torr<br /> <br />
参考文献
Bailey, Patrick D.; Brown, George R.; Korber, Fritjof; Reed, Amanda; Wilson, Robert D. Tetrahedron: Asymmetry, 1991 , vol. 2, # 12 p. 1263 - 1282
反应条件
<b>Multi-step reaction with 3 steps<br /> </b>1: 100 percent / toluene / 0.33 h / Heating<br />2: trifluoroacetic acid (TFA), H<sub>2</sub>O / dimethylformamide / 30 h / Ambient temperature<br />3: H<sub>2</sub> / 3percent Pt/C / ethyl acetate / 16 h / 760 Torr<br /> <br />
参考文献
Bailey, Patrick D.; Brown, George R.; Korber, Fritjof; Reed, Amanda; Wilson, Robert D. Tetrahedron: Asymmetry, 1991 , vol. 2, # 12 p. 1263 - 1282
反应条件
<b>Multi-step reaction with 2 steps<br /> </b>1: TFA, H<sub>2</sub>O / dimethylformamide / 30 h / Ambient temperature<br />2: H<sub>2</sub> / 3percent Pt-C / ethyl acetate / 16 h / 760 Torr / Ambient temperature<br /> <br />
参考文献
Bailey, Patrick D.; Wilson, Robert D.; Brown, George R. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 5 p. 1337 - 1340
