1: 82 percent / SOCl2 / CH2Cl2 / 2 h / Heating 2: NaHCO3 / CH2Cl2 / 0.25 h 3: 4-(aminomethyl)piperidine silica reagent / CH2Cl2 / 0.25 h 4: NaHCO3 / CH2Cl2 / 0.25 h 5: 4-(aminomethyl)piperidine silica reagent / CH2Cl2 / 0.25 h 6: NaHCO3 / CH2Cl2 / 0.25 h 7: 4-(aminomethyl)piperidine silica reagent / CH2Cl2 / 0.25 h 8: NaHCO3 / CH2Cl2 / 0.33 h 9: 58 percent / H2 / Pd/C / ethanol; ethyl acetate / 24 h / 2327.17 Torr / Ambient temperature View Scheme