2-溴-4-苯基乙酰苯合成路线 （共 108 条）
参考文献
Wrede; Rothhaas
Chemische Berichte, 1934 , vol. 67, p. 739
Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1934 , vol. 226, p. 95,97,102
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Drake; Bronitsky
Journal of the American Chemical Society, 1930 , vol. 52, p. 3715,3716, 3719
参考文献
Kondo; Suzuki
Chemische Berichte, 1936 , vol. 69, p. 2459,2463
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Suzuki
Yakugaku Zasshi, 1936 , vol. 56, p. 841,851
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Sutter; Schlittler
Helvetica Chimica Acta, 1947 , vol. 30, p. 2102,2107
反应条件
sodium hydroxide
1.) MeOH, 1h, r.t.; 2.) EtOH, 30 min, reflux; Multistep reaction;
参考文献
Teresa, J. De Pascual; Moran, Joaquin R.; Hernandez, Jose M.; Grande, M.
Phytochemistry (Elsevier), 1985 , vol. 24, # 9 p. 2071 - 2074
反应条件
sodium hydroxide
1.) MeOH, 1h, r.t.; 2.) EtOH, 30 min, reflux; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Teresa, J. De Pascual; Moran, Joaquin R.; Hernandez, Jose M.; Grande, M.
Phytochemistry (Elsevier), 1985 , vol. 24, # 9 p. 2071 - 2074
参考文献
Rutter
Journal of the American Chemical Society, 1951 , vol. 73, p. 5905
参考文献
Chadha,V.K.
Journal of the Indian Chemical Society, 1978 , vol. 55, p. 817 - 818
参考文献
Japan Tobacco Inc.
Patent: EP885869 A1, 1998 ;
反应条件
1: 100 percent / 80percent sodium hydride / hexamethylphosphoric acid triamide; various solvent(s) / 2 h / Ambient temperature
2: 94 percent / N sodium carbonate / ethanol / 0.5 h / Heating
View Scheme
参考文献
Cousse; Mouzin; Rieu; et al.
European Journal of Medicinal Chemistry, 1987 , vol. 22, # 1 p. 45 - 57
参考文献
Drake; Bronitsky
Journal of the American Chemical Society, 1930 , vol. 52, p. 3715,3716, 3719
参考文献
Drake; Bronitsky
Journal of the American Chemical Society, 1930 , vol. 52, p. 3715,3716, 3719
