1,2,4-三甲氧基苯合成路线 （共 122 条）
反应条件
1: Zn; HCl / toluene 2: PPA View Scheme
参考文献
Ameer, Farouk; Giles, Robin G. F.; Green, Ivan R.; Pearce, Rene
Synthetic Communications, 2004 , vol. 34, # 7 p. 1247 - 1258
反应条件
1: 85 percent / TMEDA, BuLi / diethyl ether; hexane / 1.) 0 deg C, 2 h, 2.) 0 deg C, 1 h 2: 97 percent / TFA, Et3SiH / 0.75 h / Ambient temperature View Scheme
参考文献
Anderson, James C.; Pearson, David J.
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 13 p. 2023 - 2029
反应条件
in acetonitrile Ambient temperature; Rate constant;
参考文献
Yagci, Y.; Schnabel, W.; Wilpert, A.; Bending, J.
Journal of the Chemical Society, Faraday Transactions, 1994 , vol. 90, # 2 p. 287 - 292
反应条件
1: 63 percent / Na / hexamethylphosphoric acid triamide / 100 °C 2: 58 percent / Na / hexamethylphosphoric acid triamide / 1 h / 100 °C View Scheme
参考文献
Testaferri, L.; Tiecco, M.; Tingoli, M.; Chianelli, D.; Montanucci, M.
Tetrahedron, 1982 , vol. 38, # 24 p. 3687 - 3692
反应条件
acetic acid 1) MeOH, electrolyzed, 15 deg C, 2 h, 2) acetone, 45 min, room temperature; Yield given. Multistep reaction. Further byproducts given;
参考文献
Henton, Daniel R.; Anderson, Keith; Manning, Michael J.; Swenton, John S.
Journal of Organic Chemistry, 1980 , vol. 45, # 17 p. 3422 - 3433
反应条件
methanol; PhI(OCOCF3)O(OCOCF3)IPh in water T=0°C; 2 h;
参考文献
Dohi, Toshifumi; Nakae, Tomofumi; Takenaga, Naoko; Uchiyama, Teruyoshi; Fukushima, Kei-Ichiro; Fujioka, Hiromichi; Kita, Yasuyuki
Synthesis, 2012 , vol. 44, # 8 p. 1183 - 1189
反应条件
dihydrogen peroxide; Ru(II)(pybox-dh)(pydic) in methanol; water T=20°C; 1 h;
参考文献
Iwasa, Seiji; Fakhruddin, Ahmad; Widagdo, Herman Setyo; Nishiyama, Hisao
Advanced Synthesis and Catalysis, 2005 , vol. 347, # 4 p. 517 - 520
反应条件
sodium in N,N-dimethyl acetamide T=100°C; 4 h;
参考文献
Synthesis, , # 9 p. 751 - 755
反应条件
N,N,N',N',N'',N''-hexamethylphosphoric triamide; sodium hydride; N-methylaniline in diethyl ether; xylene T=85°C; 6 h;
参考文献
Synthesis, , # 8 p. 638 - 640
反应条件
1: POCl3 2: H2, NaHCO3 / PtO2 View Scheme
参考文献
Birch,A.J. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1975 , p. 2492 - 2501
