1,2,4-三甲氧基苯合成路线 （共 122 条）
反应条件
1: 95 percent / I2 / 6 h / 70 °C 2: 100 percent / NaBH4 / ethanol / 1 h / 20 °C 3: 95 percent / AcONa; Ac2O / 3 h / Heating View Scheme
参考文献
Diaz, Francisco; Contreras, Leticia; Flores, Rosa; Tamariz, Joaquin; Labarrios, Fernando; et al.
Organic Preparations and Procedures International, 1991 , vol. 23, # 2 p. 133 - 138
反应条件
1: AlCl3; diethyl ether 2: aluminium chloride; diethyl ether; 1,1,2,2-tetrachloro-ethane / Behandeln des Reaktionsgemisches mit wss. Salzsaeure und Behandeln des Reaktionsprodukts mit wss. Natronlauge View Scheme
参考文献
Huls
Bulletin des Societes Chimiques Belges, 1958 , vol. 67, p. 22,30
反应条件
aluminium trichloride; diethyl ether; tetrachloroethane, 1,1,2,2-
参考文献
Huls
Bulletin des Societes Chimiques Belges, 1958 , vol. 67, p. 22,30
反应条件
1: 1,2,4-trimethoxy benzene With n-butyllithium in diethyl ether; hexane T=-10 - 20°C; Inert atmosphere; 2: carbon dioxide in diethyl ether; hexane T=-10°C; Inert atmosphere;
参考文献
Alves, Ana P. L.; Junior, Jose Augusto B. C.; Slana, Glaucia B. A.; Cardoso, Jari N.; Wang, Qiang; Lopes, Rosangela S. C.; Lopes, Claudio C.
Synthetic Communications, 2009 , vol. 39, # 20 p. 3693 - 3709
参考文献
Gilman; Thirtle
Journal of the American Chemical Society, 1944 , vol. 66, p. 858
反应条件
1: AlCl3; diethyl ether 2: aluminium chloride; diethyl ether; 1,1,2,2-tetrachloro-ethane / Behandeln des Reaktionsgemisches mit wss. Salzsaeure und Behandeln des Reaktionsprodukts mit wss. Natronlauge 3: lithium alanate; diethyl ether 4: aluminium oxide / 160 °C View Scheme
参考文献
Huls
Bulletin des Societes Chimiques Belges, 1958 , vol. 67, p. 22,30
反应条件
1: 1.) n-BuLi / 1.) THF, 20 deg C, 2.) Et2O 2: Br2 / dioxane / 1 h / Ambient temperature View Scheme
参考文献
Hoegberg, Thomas; Bengtsson, Stefan; Paulis, Tomas de; Johansson, Lars; Stroem, Peter; et al.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 4 p. 1155 - 1163
反应条件
2,6-dichloropyridine-N-oxide; [Ru(CO)(tmp)]; 4 A molecular sieve; hydrogen bromide in benzene T=40°C;
参考文献
Higuchi, Tsunehiko; Satake, Chika; Hirobe, Masaaki
Journal of the American Chemical Society, 1995 , vol. 117, # 34 p. 8879 - 8880
反应条件
dihydrogen peroxide; Ru(II)(pybox-dh)(pydic) in methanol; water T=20°C; 1 h;
参考文献
Advanced Synthesis and Catalysis, , vol. 347, # 4 p. 517 - 520
反应条件
1: POCl3 2: BCl3 3: K2CO3 View Scheme
参考文献
Jackson,A.H.; Martin,J.A.
Journal of the Chemical Society [Section] C: Organic, 1966 , p. 2222 - 2229
