1: 93 percent / Na2CO3 / methanol / 3.5 h / Ambient temperature 2: 48 percent / SeO2, t-BuOOH / 2,2,4-trimethyl-pentane / 1.) 0 deg C, 2 h, 2.) room temperature, 4 h 3: 94 percent / imidazole / dimethylformamide / 4 h / Ambient temperature 4: 1.) n-BuLi / 1.) THF, hexane, room temperature, 20 min, 2.) room temperature, 30 min 5: 88 percent / MeONa, LiAlH4 / methanol; tetrahydrofuran / 1 h / Heating 6: 99 percent / TBAF / tetrahydrofuran / 16 h / Ambient temperature 7: 1.) p-TsOH, 2.) t-BuOMe, 9-acetoxyanthracene / 1.) dioxane, H2O, 75 deg C, 4 h, 2.) irradiation, 1 h View Scheme

1: 1.) n-BuLi / 1.) THF, hexane, 50 deg C, 15 min, 2.) -15 deg C, 20 min; 0 deg C, 30 min 2: 78 percent / LiAlH4, MeONa / tetrahydrofuran; methanol / 15 h / Ambient temperature 3: 98 percent / n-Bu4NF / tetrahydrofuran / 3 h / Ambient temperature 4: 1.) PPTS, 2.) t-BuOMe, 9-acetoxyanthracene / 1.) MeCN, H2O, 70 deg C, 2.5 h, 2.) irradiation, 2 h View Scheme

<b>Multi-step reaction with 3 steps<br /> </b>1: 67 percent / Sm, HgCl₂ / tetrahydrofuran / 31 - 40 &deg;C<br />2: 82 percent / PCC / CH₂Cl₂ / 3 h / Ambient temperature<br />3: 1.) t-BuOK / 1.) THF, room temperature, 2 h, 2.) 30 min<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 82 percent / PCC / CH₂Cl₂ / 3 h / Ambient temperature<br />2: 1.) t-BuOK / 1.) THF, room temperature, 2 h, 2.) 30 min<br /> <br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: 96 percent / Et₃N, (Ph₃P)2PdCl₂, CuI / benzene / 0.33 h / 40 &deg;C<br />2: 67 percent / Sm, HgCl₂ / tetrahydrofuran / 31 - 40 &deg;C<br />3: 82 percent / PCC / CH₂Cl₂ / 3 h / Ambient temperature<br />4: 1.) t-BuOK / 1.) THF, room temperature, 2 h, 2.) 30 min<br /> <br /> &nbsp;