N-(对甲苯磺酰)-L-苯丙氨酸合成路线 （共 22 条）
参考文献
Tetrahedron Letters, , vol. 39, # 39 p. 7101 - 7104
反应条件
dimethylsulfide; borane in tetrahydrofuran T=25°C; 48 h;
参考文献
Journal of the American Chemical Society, , vol. 102, # 18 p. 5960 - 5962
反应条件
1: LiAlH4 2: TsCl; Et3N; 4-dimethylaminopyridine View Scheme
参考文献
Alonso, Diego A.; Andersson, Pher G.
Journal of Organic Chemistry, 1998 , vol. 63, # 25 p. 9455 - 9461
反应条件
1: LiAlH4 / tetrahydrofuran / 12 h / Ambient temperature 2: p-toluenesulfonyl chloride, Et3N / CH2Cl2 / 12 h / Ambient temperature 3: 8 percent / Na / liquid ammonia; tetrahydrofuran / 0.75 h / -78 °C View Scheme
参考文献
Alonso, Diego A.; Andersson, Pher G.
Journal of Organic Chemistry, 1998 , vol. 63, # 25 p. 9455 - 9461
反应条件
1: (COCl)2, DMF / CH2Cl2 / 3 h / Ambient temperature 2: tetrahydrofuran; diethyl ether / 4 h / 0 - 20 °C View Scheme
参考文献
Wang, Jianbo; Hou, Yihua
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 12 p. 1919 - 1923
反应条件
thionyl chloride in chloroform T=20°C; 3 h; Reflux;
参考文献
Ghosh, Debashis; Sadhukhan, Arghya; Maity, Nabin Ch.; Abdi, Sayed H. R.; Khan, Noor-Ul H.; Kureshy, Rukhsana I.; Bajaj, Hari C.
RSC Advances, 2014 , vol. 4, # 24 p. 12257 - 12265
反应条件
1: LiAlH4 / tetrahydrofuran / 12 h / Ambient temperature 2: p-toluenesulfonyl chloride, Et3N / CH2Cl2 / 12 h / Ambient temperature 3: 47 percent / Na / liquid ammonia; tetrahydrofuran / 0.75 h / -78 °C View Scheme
参考文献
Alonso, Diego A.; Andersson, Pher G.
Journal of Organic Chemistry, 1998 , vol. 63, # 25 p. 9455 - 9461
反应条件
hydrogen bromide in acetic acid
参考文献
Beresford, Kenneth J. M.; Church, Nicola J.; Young, Douglas W.
Organic and Biomolecular Chemistry, 2006 , vol. 4, # 15 p. 2888 - 2897
反应条件
N,N'-dimethyl-N,N'-propyleneurea; samarium diiodide in tetrahydrofuran 11 h; Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Vedejs, Edwin; Lin, Shouzhong
Journal of Organic Chemistry, 1994 , vol. 59, # 7 p. 1602 - 1603
反应条件
1: LiAlH4 / tetrahydrofuran / 12 h / Ambient temperature
2: p-toluenesulfonyl chloride, Et3N / CH2Cl2 / 12 h / Ambient temperature
3: 20 percent / Mg / methanol / 0.5 h / Ambient temperature
View Scheme
参考文献
Alonso, Diego A.; Andersson, Pher G.
Journal of Organic Chemistry, 1998 , vol. 63, # 25 p. 9455 - 9461
