1.1: hydrogenchloride / anhydrous dichloroethane; water / 0 - 5 °C / pH 2.5 1.2: 14.25 h / 0 - 30 °C 2.1: N-bromosuccinmide; phosphoric acid / water; tetrahydrofuran / 1.25 h / 0 - 5 °C 3.1: sodium azide / ethylene glycol / 20 h / 80 - 85 °C 4.1: triethylamine; 2-hydroxy-pyridine / 16 h / 85 - 90 °C 5.1: hydrogen; ethanolamine / palladium 10 on activated carbon / isopropyl alcohol / 3 h View Scheme

1.1: hydrogenchloride / anhydrous dichloroethane; water / 0 - 5 °C / pH 2.5 1.2: 14.25 h / 0 - 30 °C 2.1: N-bromosuccinmide; phosphoric acid / water; tetrahydrofuran / 1.25 h / 0 - 5 °C 3.1: sodium azide / ethylene glycol / 20 h / 80 - 85 °C 4.1: triethylamine; 2-hydroxy-pyridine / 16 h / 85 - 90 °C View Scheme