(5-氰基吡啶-3-基)-甲醇合成路线 （共 6 条）
反应条件
1: in pyridine T=160°C; 20 h; 2: With ammonia; ammonium chloride in pyridine; water T=20°C; 2 h;
参考文献
SANOFI
Patent: US2011/294788 A1, 2011 ;
Location in patent: Page/Page column 24 ;
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=-78°C; 1.05 h; 2: With sodium hydroxide; water in tetrahydrofuran
参考文献
ELI LILLY AND COMPANY
Patent: WO2005/66126 A1, 2005 ;
Location in patent: Page/Page column 66-67 ;
WO 2005/066126 A1
反应条件
in N,N-dimethyl-formamide T=170°C; 1.75 h;
参考文献
Winter, Joachim; Retey, Janos
Chemistry - A European Journal, 1997 , vol. 3, # 3 p. 410 - 416
反应条件
in pyridine; chloroform; ethyl acetate
反应条件
1.1: chloroformic acid ethyl ester; 4-methyl-morpholine / tetrahydrofuran / 0.33 h / -10 °C / Inert atmosphere 1.2: 13.5 h / -70 - 20 °C 2.1: pyridine / 20 h / 160 °C 2.2: 2 h / 20 °C View Scheme
反应条件
manganese(IV) oxide in dichloromethane T=60°C; 98 h;
参考文献
Cytovia, Inc.
Patent: US2006/104998 A1, 2006 ;
Location in patent: Page/Page column 16 ;
US 20060104998 A1
