1,1-二杂苯[B]硫代苯甲基氯草酸酯合成路线 （共 13 条）
反应条件
triethyl amine hydrochloride in tetrahydrofuran T=40°C; 3 h;
参考文献
Carpino, Louis A.; Abdel-Maksoud, Adel Ali; Ionescu, Dumitru; Mansour; Zewail, Mohamed A.
Journal of Organic Chemistry, 2007 , vol. 72, # 5 p. 1729 - 1736
反应条件
1: 2.) NaBH4 / 2.) MeOH 2: 75 percent / sodium perborate tetrahydrate / acetic acid / 45 - 50 °C 3: 36.1 g / tetrahydrofuran / -30 - 20 °C View Scheme
参考文献
Carpino, Louis A.; Ismail, Mohamed; Truran, George A.; Mansour; Iguchi, Shin; Ionescu, Dumitru; El-Faham, Ayman; Riemer, Christoph; Warrass, Ralf
Journal of Organic Chemistry, 1999 , vol. 64, # 12 p. 4324 - 4338
反应条件
1: 75 percent / sodium perborate tetrahydrate / acetic acid / 45 - 50 °C 2: 36.1 g / tetrahydrofuran / -30 - 20 °C View Scheme
参考文献
Carpino, Louis A.; Ismail, Mohamed; Truran, George A.; Mansour; Iguchi, Shin; Ionescu, Dumitru; El-Faham, Ayman; Riemer, Christoph; Warrass, Ralf
Journal of Organic Chemistry, 1999 , vol. 64, # 12 p. 4324 - 4338
反应条件
1: 1.) n-BuLi / 1.) THF, hexane, -30 deg C, 2 h, 2.) -78 deg C to room temperature, overnight 2: 75 percent / sodium perborate tetrahydrate / acetic acid / 45 - 50 °C 3: 36.1 g / tetrahydrofuran / -30 - 20 °C View Scheme
参考文献
Carpino, Louis A.; Ismail, Mohamed; Truran, George A.; Mansour; Iguchi, Shin; Ionescu, Dumitru; El-Faham, Ayman; Riemer, Christoph; Warrass, Ralf
Journal of Organic Chemistry, 1999 , vol. 64, # 12 p. 4324 - 4338
反应条件
in tetrahydrofuran T=-30 - 20°C;
参考文献
Carpino, Louis A.; Ismail, Mohamed; Truran, George A.; Mansour; Iguchi, Shin; Ionescu, Dumitru; El-Faham, Ayman; Riemer, Christoph; Warrass, Ralf
Journal of Organic Chemistry, 1999 , vol. 64, # 12 p. 4324 - 4338
反应条件
1: 74 percent / CH2Cl2 / 20 h 2: 90.4 percent / NaHCO3 / acetone / Ambient temperature View Scheme
参考文献
Carpino, Louis A.; Ismail, Mohamed; Truran, George A.; Mansour; Iguchi, Shin; Ionescu, Dumitru; El-Faham, Ayman; Riemer, Christoph; Warrass, Ralf
Journal of Organic Chemistry, 1999 , vol. 64, # 12 p. 4324 - 4338
反应条件
chloro-trimethyl-silane; N-ethyl-N,N-diisopropylamine 1.) CH2Cl2, reflux, 1 h, 2.) 0 deg C 20 min,; room temperature, 1-1.5 h; Yield givenMultistep reaction;
参考文献
Carpino, Louis A.; Ismail, Mohamed; Truran, George A.; Mansour; Iguchi, Shin; Ionescu, Dumitru; El-Faham, Ayman; Riemer, Christoph; Warrass, Ralf
Journal of Organic Chemistry, 1999 , vol. 64, # 12 p. 4324 - 4338
反应条件
chloro-trimethyl-silane; N-ethyl-N,N-diisopropylamine 1.) CH2Cl2, reflux, 1 h, 2.) 0 deg C 20 min,; room temperature, 1-1.5 h; Yield givenMultistep reaction;
参考文献
Carpino, Louis A.; Ismail, Mohamed; Truran, George A.; Mansour; Iguchi, Shin; Ionescu, Dumitru; El-Faham, Ayman; Riemer, Christoph; Warrass, Ralf
Journal of Organic Chemistry, 1999 , vol. 64, # 12 p. 4324 - 4338
反应条件
chloro-trimethyl-silane; N-ethyl-N,N-diisopropylamine 1.) CH2Cl2, reflux, 1 h, 2.) 0 deg C 20 min,; room temperature, 1-1.5 h; Yield givenMultistep reaction;
参考文献
Carpino, Louis A.; Ismail, Mohamed; Truran, George A.; Mansour; Iguchi, Shin; Ionescu, Dumitru; El-Faham, Ayman; Riemer, Christoph; Warrass, Ralf
Journal of Organic Chemistry, 1999 , vol. 64, # 12 p. 4324 - 4338
反应条件
1: 74 percent / CH2Cl2 / 20 h 2: 92 percent / Et3N / acetonitrile; H2O / 0.75 h / Ambient temperature; pH 8.5-9 View Scheme
参考文献
Carpino, Louis A.; Ismail, Mohamed; Truran, George A.; Mansour; Iguchi, Shin; Ionescu, Dumitru; El-Faham, Ayman; Riemer, Christoph; Warrass, Ralf
Journal of Organic Chemistry, 1999 , vol. 64, # 12 p. 4324 - 4338
