1: NaH, CuBr-SMe2, collidine / 8 h / 130 °C 2: 98 percent / H2 / 10percent Pd/C / methanol / 6 h / 25 °C / 760 Torr 3: 53 percent / EDCI, HOBt*H2O / dimethylformamide / 16 h / 25 °C 4: LiOH*H2O / tetrahydrofuran; methanol; H2O / 2 h / 25 °C 5: HCl / ethyl acetate / 1 h / 25 °C 6: 58 percent / DPPA, NaHCO3 / dimethylformamide / 72 h / 0 °C 7: 57 percent / BBr3 / CH2Cl2 / 3 h / -78 - 0 °C View Scheme

1: NaH, CuBr-SMe2, collidine / 8 h / 130 °C 2: 98 percent / H2 / 10percent Pd/C / methanol / 6 h / 25 °C / 760 Torr 3: 53 percent / EDCI, HOBt*H2O / dimethylformamide / 16 h / 25 °C 4: LiOH*H2O / tetrahydrofuran; methanol; H2O / 2 h / 25 °C 5: HCl / ethyl acetate / 1 h / 25 °C 6: 58 percent / DPPA, NaHCO3 / dimethylformamide / 72 h / 0 °C View Scheme