3-环己烯氨基甲酸叔丁酯合成路线 （共 15 条）
反应条件
copper(l) chloride in toluene
T=100°C; 2 h;
参考文献
Kapferer, Peter; Vasella, Andrea
Helvetica Chimica Acta, 2004 , vol. 87, # 11 p. 2764 - 2789
反应条件
1: trans-1-amino-4-cyclohexanol With thionyl chloride in chloroform
Reflux;
2: di-tert-butyl dicarbonate With potassium carbonate; triethylamine in chloroform
T=0 - 20°C; 11 h;
参考文献
Alvarez-Perez, Monica; Marco-Contelles, Jose
Synthesis, 2009 , # 21 p. 3649 - 3653
反应条件
1H-imidazole; iodine; triphenylphosphine in dichloromethane
T=20°C; Inert atmosphere;
参考文献
Alvarez-Perez, Monica; Marco-Contelles, Jose
Synthesis, 2009 , # 21 p. 3649 - 3653
反应条件
1: chromium(VI) oxide; sulfuric acid / acetone / 0 °C / |Inert atmosphere
2: diphenyl phosphoryl azide; triethylamine / toluene / 95 °C / |Inert atmosphere
3: copper(l) chloride / |Inert atmosphere
View Scheme
参考文献
Walker, P. Ross; Campbell, Craig D.; Suleman, Abid; Carr, Greg; Anderson, Edward A.
Angewandte Chemie - International Edition, 2013 , vol. 52, # 35 p. 9139 - 9143
Angew. Chem., 2013 , vol. 125, # 36 p. 9309 - 9313
反应条件
diphenylphosphoranyl azide; triethylamine
Curtius rearrangement; 48 h; Heating;
参考文献
Gomez-Sanchez, Elena; Marco-Contelles, Jose
Tetrahedron, 2005 , vol. 61, # 5 p. 1207 - 1219
