(3beta,5Z,7E)-3-(叔-丁基二甲基硅烷基氧基)-9,10-开环胆甾-5,7,10(19)-三烯-24-羧酸甲酯合成路线 （共 8 条）
反应条件
n-butyllithium T=-78°C;
参考文献
Mascarenas, Jose L.; Perez-Sestelo, Jose; Castedo, Luis; Mourino, Antonio
Tetrahedron Letters, 1991 , vol. 32, # 24 p. 2813 - 2816
反应条件
copper(l) iodide; zinc in ethanol; water 1.33333 h; ultrasonically induced reaction;
参考文献
Perez-Sestelo, J.; Mascarennas, J. L.; Castedo, L.; Mourinno, A.
Tetrahedron Letters, 1994 , vol. 35, # 2 p. 275 - 278
反应条件
1: 95 percent / n-BulI / hexane; tetrahydrofuran / 1.) -78 deg C, 30 min; 2.) -92 deg C 2: 50 percent / CuI, Zn / ethanol; H2O / 1.33 h / ultrasonically induced reaction View Scheme
参考文献
Perez-Sestelo, J.; Mascarennas, J. L.; Castedo, L.; Mourinno, A.
Tetrahedron Letters, 1994 , vol. 35, # 2 p. 275 - 278
反应条件
1: 95 percent / n-BulI / hexane; tetrahydrofuran / 1.) -78 deg C, 30 min; 2.) -92 deg C 2: 50 percent / CuI, Zn / ethanol; H2O / 1.33 h / ultrasonically induced reaction View Scheme
参考文献
Perez-Sestelo, J.; Mascarennas, J. L.; Castedo, L.; Mourinno, A.
Tetrahedron Letters, 1994 , vol. 35, # 2 p. 275 - 278
反应条件
1: 75 percent / CuI, Zn / ethanol; H2O / 0.67 h / Ambient temperature; sonicated 2: 99 percent / pyridinium dichromate 3: 89 percent / n-butyllithium / -78 °C View Scheme
参考文献
Mascarenas, Jose L.; Perez-Sestelo, Jose; Castedo, Luis; Mourino, Antonio
Tetrahedron Letters, 1991 , vol. 32, # 24 p. 2813 - 2816
反应条件
1: 99 percent / pyridinium dichromate 2: 89 percent / n-butyllithium / -78 °C View Scheme
参考文献
Mascarenas, Jose L.; Perez-Sestelo, Jose; Castedo, Luis; Mourino, Antonio
Tetrahedron Letters, 1991 , vol. 32, # 24 p. 2813 - 2816
反应条件
tetrabutyl ammonium fluoride 1. diethyl ether, -78 deg C, 2. THF; Yield given. Multistep reaction;
参考文献
Mascarenas, Jose L.; Perez-Sestelo, Jose; Castedo, Luis; Mourino, Antonio
Tetrahedron Letters, 1991 , vol. 32, # 24 p. 2813 - 2816
反应条件
tetrabutyl ammonium fluoride 1. diethyl ether, -78 deg C, 2. THF; Yield given. Multistep reaction;
参考文献
Mascarenas, Jose L.; Perez-Sestelo, Jose; Castedo, Luis; Mourino, Antonio
Tetrahedron Letters, 1991 , vol. 32, # 24 p. 2813 - 2816
