6-氯-1-(四氢-2H-吡喃-2-基)-1H-吡唑并[4,3-c]吡啶合成路线 (共 2 条)
反应条件
p-toluenesulfonyl chloride in 1,4-dioxane T=110°C;
参考文献
F. HOFFMANN-LA ROCHE AG; GENENTECH, INC.; DO, Steven; HU, Huiyong; KOLESNIKOV, Aleksandr; TSUI, Vickie, H.; WANG, Xiaojing
Patent: WO2014/1377 A1, 2014 ;
Location in patent: Page/Page column 121; 122 ;
反应条件
methanesulfonic acid in tetrahydrofuran; dichloromethane; ethyl acetate
参考文献
Incyte Corporation; Zhuo, Jincong; Xu, Meizhong; Qian, Ding-Quan
Patent: US2014/171405 A1, 2014 ;
Location in patent: Page/Page column ;