1: hydrogenchloride; water / 1,4-dioxane / 24 h / 20 °C 2: sodium hydrogencarbonate / 1,4-dioxane / 3 h / 20 °C 3: 10 palladium on activated charcoal; hydrogen / ethyl acetate / 14 h / 20 °C / 760.05 Torr 4: lithium hydroxide hydrate / tetrahydrofuran; methanol; water / 14 h / 20 °C View Scheme