1: thionyl chloride; silver nitrate / tetrahydrofuran / 25 °C / Inert atmosphere 2: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / -78 °C / Inert atmosphere View Scheme

1: thionyl chloride; silver nitrate / tetrahydrofuran / 25 °C / Inert atmosphere 2: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.2 h / -78 - 20 °C / Inert atmosphere View Scheme

1: thionyl chloride; silver nitrate / tetrahydrofuran / 25 °C / Inert atmosphere 2: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.2 h / -78 - 20 °C / Inert atmosphere View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11343078', constants.ctx, '0')">sodium tetrahydroborate</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1098229', constants.ctx, '0')">methanol</a> <br />T=20&deg;C;&nbsp;6&nbsp;h;&nbsp;&nbsp;Inert atmosphere;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / 1 h / 0 &deg;C / Inert atmosphere<br />2: sodium tetrahydroborate / methanol / 6 h / 20 &deg;C / Inert atmosphere<br /> <br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 4-(N,N-dimethlyamino)pyridine; triethylamine / dichloromethane / 1 h / 0 &deg;C / Inert atmosphere<br />2: sodium tetrahydroborate / methanol / 6 h / 20 &deg;C / Inert atmosphere<br /> <br /> &nbsp;