(1R,2S,3S,5S)-3-(4-碘苯基)-8-甲基-8-氮杂双环[3.2.1]辛烷-2-羧酸甲酯合成路线

135416-43-2(1R,2S,3S,5S)-3-(4-碘苯基)-8-甲基-8-氮杂双环[3.2.1]辛烷-2-羧酸甲酯

参考文献

Emory university
Patent: US5864038 A1, 1999 ;
US 5864038 A

50372-80-0(1R,2S,3S,5S)-8-甲基-3-苯基-8-氮杂双环[3.2.1]辛烷-2-羧酸甲酯

135416-43-2(1R,2S,3S,5S)-3-(4-碘苯基)-8-甲基-8-氮杂双环[3.2.1]辛烷-2-羧酸甲酯

参考文献

Neumeyer; Wang; Milius; Baldwin; Zea-Ponce; Hoffer; Sybirska; Al-Tikriti; Charney; Malison; Laruelle; Innis
Journal of Medicinal Chemistry, 1991 , vol. 34, # 10 p. 3144 - 3146

17878-43-2

135416-43-2(1R,2S,3S,5S)-3-(4-碘苯基)-8-甲基-8-氮杂双环[3.2.1]辛烷-2-羧酸甲酯

参考文献

Gu, Xiao-Hui; Zong, Rushi; Kula, Nora S.; Baldessarini, Ross J.; Neumeyer, John L.
Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 23 p. 3049 - 3053

481-37-8芽子碱

135416-43-2(1R,2S,3S,5S)-3-(4-碘苯基)-8-甲基-8-氮杂双环[3.2.1]辛烷-2-羧酸甲酯

参考文献

Tamagnan, Gilles; Baldwin, Ronald M.; Kula, Nora S.; Baldessarini, Ross J.; Innis, Robert B.
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 16 p. 1783 - 1785

50-36-2古卡因

135416-43-2(1R,2S,3S,5S)-3-(4-碘苯基)-8-甲基-8-氮杂双环[3.2.1]辛烷-2-羧酸甲酯

参考文献

Tamagnan, Gilles; Baldwin, Ronald M.; Kula, Nora S.; Baldessarini, Ross J.; Innis, Robert B.
Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 16 p. 1783 - 1785

135416-43-2(1R,2S,3S,5S)-3-(4-碘苯基)-8-甲基-8-氮杂双环[3.2.1]辛烷-2-羧酸甲酯

参考文献

Chen; Kilts; Camp; Ely; Keil; Malveaux; Votaw; Hoffman; Goodman
Journal of Labelled Compounds and Radiopharmaceuticals, 1999 , vol. 42, # SUPPL. 1 p. S400-S402

135416-43-2(1R,2S,3S,5S)-3-(4-碘苯基)-8-甲基-8-氮杂双环[3.2.1]辛烷-2-羧酸甲酯

141807-58-1

参考文献

Peng, Xuemei; Zhang, Ao; Kula, Nora S.; Baldessarini, Ross J.; Neumeyer, John L.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 22 p. 5635 - 5639

135416-43-2(1R,2S,3S,5S)-3-(4-碘苯基)-8-甲基-8-氮杂双环[3.2.1]辛烷-2-羧酸甲酯

参考文献

Emory university
Patent: US5864038 A1, 1999 ;
US 5864038 A

135416-43-2(1R,2S,3S,5S)-3-(4-碘苯基)-8-甲基-8-氮杂双环[3.2.1]辛烷-2-羧酸甲酯

146145-21-3(1R,2S,3S)-3-(4-碘苯基)-8-甲基-8-氮杂双环[3.2.1]辛烷-2-羧酸丙-2-基酯

参考文献

Carroll; Abraham; Lewin; Parham; Boja; Kuhar
Journal of Medicinal Chemistry, 1992 , vol. 35, # 13 p. 2497 - 2500

135416-43-2(1R,2S,3S,5S)-3-(4-碘苯基)-8-甲基-8-氮杂双环[3.2.1]辛烷-2-羧酸甲酯

155337-52-3RTI-83

参考文献

Blough, Bruce E.; Abraham, Philip; Lewin, Anita H.; Kuhar, Michael J.; Boja, John W.; Ivy Carroll
Journal of Medicinal Chemistry, 1996 , vol. 39, # 20 p. 4027 - 4035