1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 - 20 °C / Inert atmosphere 2: trifluoroacetic acid / toluene / 48 h / 20 °C 3: triethylamine / dichloromethane / 1 h / 20 °C 4: potassium phosphate; tetrakis(triphenylphosphine) palladium(0); potassium bromide / 1,4-dioxane / 2 h / Inert atmosphere; Reflux View Scheme

1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / -78 - 20 °C / Inert atmosphere 2: trifluoroacetic acid / toluene / 48 h / 20 °C 3: triethylamine / dichloromethane / 1 h / 20 °C 4: potassium phosphate; tetrakis(triphenylphosphine) palladium(0); potassium bromide / 1,4-dioxane / 1 h / Inert atmosphere; Reflux View Scheme