反应条件
1: n-butyllithium / hexane; tetrahydrofuran / Cooling 2: pyridinium chlorochromate / dichloromethane / 20 °C 3: dimethylsulfide borane complex; (R)-tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c]-[1,3,2]oxazaborole / toluene; tetrahydrofuran / -30 - -25 °C 4: 1H-imidazole / dichloromethane / 20 °C 5: dichloromethane / 20 °C / Inert atmosphere 6: potassium carbonate; hydrogen / palladium 10 on activated carbon / ethanol / 20 °C 7: sodium hydroxide; water; sodium tetrahydroborate / ethanol 8: hydrogen / palladium 10 on activated carbon / acetic acid 9: potassium carbonate; tetra-(n-butyl)ammonium iodide / ethanol / 20 °C / Reflux 10: sodium hydroxide / ethanol; water View Scheme