1: 97 percent / triethylamine, 4-dimethylaminopyridine (DMAP) / CH2Cl2 / 2 h / Ambient temperature 2: 1.) sodium hydride / 1.) DMF, 80 deg C, 2.5 h, 2.) DMF, 80 deg C, 24 h 3: 71 percent / phenol, 33percent HBr in acetic acid / 60 h / 80 °C View Scheme

1: 98.4 percent / pyridine 2: 45 percent / Na2CO3 / acetonitrile / 72 h / Heating 3: 86.2 percent / LiAlH4 / tetrahydrofuran / 96 h / Heating View Scheme

1: 97 percent / triethylamine, 4-dimethylaminopyridine (DMAP) / CH2Cl2 / 2 h / Ambient temperature 2: 1.) sodium hydride / 1.) DMF, 80 deg C, 2.5 h, 2.) DMF, 80 deg C, 24 h View Scheme